To segment your customers based on their region, follow the below steps:
Open the Single Customer View module, then click Contact Segmentation.
From the Data Tree nodes list, drag and drop the Nearby Contacts (wizard).
From the pop-up, add the needed details:
Select the location that you will compare to it.
Select the calculation mode:
Drive Time: Select one or more locations and choose from predefined time ranges from 5 to 40 minutes.
Radius: Select one or more locations and choose from predefined distance ranges from 1 to 20 miles.
Select the drive time or radius details.
Click Next, add a title to your selection, then click Next.